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While the COVID-19 pandemic morphs into less malignant forms, the virus has spawned a series of poorly understood, post-infection symptoms with staggering ramifications, i. e., long COVID (LC). This bibliometric study profiles the rapidly growing LC research domain [5,243 articles from PubMed and Web of Science (WoS)] to make its knowledge content more accessible. The article addresses What? Where? Who? and When? questions. A 13-topic Concept Grid presents bottom-up topic clusters. We break out those topics with other data fields, including disciplinary concentrations, topical details, and information on research “players” (countries, institutions, and authors) engaging in those topics. We provide access to results via a Dashboard website. We find a strongly growing, multidisciplinary LC research domain. That domain appears tightly connected based on shared research knowledge. However, we also observe notable concentrations of research activity in different disciplines. Data trends over 3 years of LC research suggest heightened attention to psychological and neurodegenerative symptoms, fatigue, and pulmonary involvement. 

Covid-19 has been an unprecedented challenge that disruptively reshaped societies and brought a massive amount of novel knowledge to the scientific community. However, as this knowledge flood has surged, researchers have been disadvantaged by not having access to a platform that can quickly synthesize rapidly emerging information and link the expertise it contains to established knowledge foundations. Aiming to fill this gap, in this paper we propose a research framework that can assist scientists in identifying, retrieving, and understanding Covid-19 knowledge from the ocean of scholarly articles. Incorporating Principal Component Decomposition (PDC), a knowledge model based on text analytics, and hierarchical topic tree analysis, the proposed framework profiles the research landscape, retrieves topic-specific knowledge and visualizes knowledge structures. Addressing 127,971 Covid-19 research papers from PubMed, our PCD topic analysis identifies 35 research hotspots, along with their correlations and trends. The hierarchical topic tree analysis further segments the knowledge landscape of the whole dataset into clinical and public health branches at a macro level. To supplement this analysis, we also built a knowledge model from research papers on vaccinations and fetched 92,286 pre-Covid publications as the established knowledge foundation for reference. The hierarchical topic tree analysis results on the retrieved papers show multiple relevant biomedical disciplines and four future research topics: monoclonal antibody treatments, vaccinations in diabetic patients, vaccine immunity effectiveness and durability, and vaccination-related allergic sensitization.